DNA Vectors
BIOHIPPO AAV-DBH-Cre-WPRE-hGH-polyA
Recombinant adeno associated virus expressing Cre under the DBH promoter with WPRE and hGH polyA elements. The Cre and Dre logic configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
BIOHIPPO AAV-VGAT1-EGFP-WPRE-hGH-polyA
Recombinant adeno associated virus expressing EGFP under the VGAT1 promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
IBA LifeSciences StrGate Acptr Vctr pASG-IBA4
The pASG-IBA4 vector is designed for expression of recombinant proteins with an N-terminal Strep-tagII in E. coli. The vector carries an ampicillin resistance cassette for selection of transformed E. coli cells, F1 and ColE1 origin for a high plasmid copy number, the inducible tetracycline promoter/operator for the regulated expression of proteins, and the ompA signal for periplasmic secretion of the recombinant protein. Expression of the protein is induced by addition of anhydrotetracycline, which is a derivative of tetracycline that does not exhibit antibiotic activity. During the secretion into the periplasmic space the ompA signal sequence will be cleaved off. Please note that cloning into pASG-IBA Acceptor Vectors compulsorily requires the restriction enzyme Esp3I since no other MCS for the integration of a gene of interest is available. In addition to the direct cloning of the gene of interest into pASG-IBA vectors with Esp3I, another option via Entry Vector is possible.
Vector Biolabs Sus scrofa MMP9 shRNA Adenovirus (Ad-S-MMP9-shRNA)
This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown Sus scrofa MMP9 gene. The shRNA expression is driven by an U6 promoter.
The knockdown of this Sus scrofa gene was validated by PCR in IPI21 cells.
Vector Biolabs b-gal/LacZ Adenovirus (Ad-CMV-b-Gal)
beta-galactosidase / LacZ recombinant adenovirus
Vector Biolabs pre-synthesized DNA vector
v-myb myeloblastosis viral oncogene homolog (avian) Adenovirus (Ad-c-Myb)
Vector Biolabs Luciferase RNAi Adenovirus (Ad-U6-Luc-RNAi)
RNAi adenovirus targeting the Luciferase. Generally used as a RNAi control adenovirus.
Vector Biolabs Caspase 9 (dn) Adenovirus (Ad-CMV-Caspase 9 (DN))
This adenovirus contains a Caspase 9 (C287A mutant).
Vector Biolabs Rap guanine nucleotide exchange factor (GEF) 3 Adenovirus (Ad-EPAC1)
Epac (exchange protein directly activated by cAMP; also designated cAMP-GEFI) and Epac2 (also designated cAMP-GEFII) compose a novel family of cyclic AMP activated guanine-nucleotide exchange factors (GEFs). Both Epac and Epac2 contain cAMP-binding motifs and a motif common to Ras superfamily GEFs. Epac and Epac2 both function to activate Rap1, a Ras-like GTPase that is known to suppress the oncogenic transformation of cells by Ras. Epac is ubiquitously expressed, whereas Epac2 is primarily expressed in the brain and adrenal glands.
Vector Biolabs Baculoviral IAP repeat-containing 4 Adenovirus (Ad-BIRC4/XIAP)
The protein encoded by this gene is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. Similar to API1, BIRC4 inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. BIRC4 also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.